Article: Spatial Gene-Expression Gradients Underlie Prominent Heterogeneity of CA1 Pyramidal Neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Cembrowski MS; Bachman JL; Wang L; Sugino K; Shields BC; Spruston N Neuron, 2016
Dorsal (n=46) | Ventral (n=31) | p value | |
---|---|---|---|
(mean +/- SEM) | (mean +/- SEM) | ||
Rn (MOhm) | 107 +/- 3 | 179 +/- 15 | <1e-6 |
RMP (mV) | -66.6 +/- 0.3 | -68.6 +/- 0.5 | <0.001 |
AHP amplitude (mV) | -0.776 +/- 0.024 | -0.931 +/- 0.04 | <0.01 |
First spike amplitude (mV) | 98.1 +/- 0.5 | 95.8 +/- 0.7 | <0.01 |
Sag ratio | 0.709 +/- 0.004 | 0.734 +/- 0.008 | <0.01 |
First spike threshold (mV) | -52.4 +/- 0.4 | -50.2 +/- 8 | <0.01 |
Second spike threshold (mV) | -38.8 +/- 0.5 | -36.6 +/- 0.9 | <0.05 |
First spike maximum falling dV/dt (mV/ms) | -112 +/- 1 | -116 +/- 1 | <0.05 |
Second spike maximum falling dV/dt (mV/ms) | -70.8 +/- 1.5 | -75.9 +/- 2.2 | n.s. |
ADP amplitude (mV) | 28.3 +/- 0.4 | 29.6 +/- 0.7 | n.s. |
Second spike amplitude (mV) | 73.7 +/- 1.3 | 69.9 +/- 2.0 | n.s. |
Second spike FWHM (ms) | 1.34 +/- 0.02 | 1.28 +/- 0.03 | n.s. |
Subthreshold dV/dt (mV/ms) | 22.5 +/- 1.1 | 21.6 +/- 1.6 | n.s. |
Spike 1 FWHM (ms) | 0.901 +/- 0.001 | 0.895 +/- 0.017 | n.s. |
First spike maximum rising dV/dt (mV/ms) | 662 +/- 12 | 656 +/- 17 | n.s. |
Second spike maximum rising dV/dt (mV/ms) | 263 +/- 11 | 258 +/- 17 | n.s. |
Related to Fig. 3. Summary of the electrophysiological parameters profiled for dorsal and ventral CA1 pyramidal cells. Table combines positive and negative Vipr2-RFP cells: |